SCHEMBL69287

SCHEMBL69287

Oc1ccc(C(Cc2ccccc2)(c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.54
ESR1 P03372 8/20 0.52
ESR2 Q92731 7/20 0.52
CYP1A2 P05177 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2C9 P11712 2/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP19A1 P11511 1/20 0.49
HIF1A Q16665 2/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
LMNA P02545 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
KCNA5 P22460 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1880947 0.96 ESR1 (0.53) KIF11ESR1ESR2CYP1A2CYP2C19
SCHEMBL11139797 0.96 ESR1 (0.53) KIF11ESR1ESR2CYP1A2CYP2C19
SCHEMBL8520412 0.94 ESR1 (0.50) KIF11ESR1ESR2CYP1A2CYP2C19
Phenol SCHEMBL28598393 0.94 CYP1A2 (0.54) KIF11ESR1ESR2CYP1A2CYP2C19
SCHEMBL156830 0.87 ESR1 (0.61) ESR1ESR2CYP3A4LMNASLC6A2
SCHEMBL126749 0.87 CYP2C9 (0.58) KIF11CYP1A2CYP2C19CYP3A4CYP2C9
SCHEMBL10556172 0.84 CYP2C9 (0.56) KIF11CYP1A2CYP2C19CYP3A4CYP2C9
SCHEMBL30797203 0.84 CYP2C9 (0.56) KIF11CYP1A2CYP2C19CYP3A4CYP2C9
SCHEMBL9449506 0.81 CYP1A2 (0.50) KIF11ESR1ESR2CYP1A2CYP2C19
SCHEMBL68967 0.81 KIF11 (0.51) KIF11ESR1ESR2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4463163-A Polycarbonate from 4,4'-bis (4-hydroxyphenyl thio)biphenyls MOBAY CHEMICAL CORPORATION (US) 1984-07-31 US claimed
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
EP-1891142-B1 OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS CIBA HOLDING INC (CH) 2014-12-03 EP disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-8013047-B2 Oligo- and poly-carbonates terminated with silicon containing groups as surface modifiers BASF SE Ludwigshafen (DE) 2011-09-06 US disclosed
US-7947767-B2 Electret materials BASF SE (DE) 2011-05-24 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-7790807-B2 polycarbonate endcapped with perfluoroalkanol (Zonyl\") incorporated into a polyester, polyacrylate, polymethacrylate or polypropylene via extrusion; self cleaning; antisoiling, oil resistance, solvent resistance, chemical resistance, scratch resistance, hydrophobic; molding material CIBA SPECIALTY CHEMICALS CORP. (US) 2010-09-07 US disclosed
US-20100210800-A1 METHOD OF PREPARING ETHYLENE POLYMERS BY CONTROLLED HIGH PRESSURE POLYMERIZATION CIBA CORPORATION (US) 2010-08-19 US disclosed
WO-1997030105-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-08-21 WO disclosed
EP-0785967-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES Ciba SC Holding AG (CH) 1997-07-30 EP disclosed
EP-0748346-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS Ciba SC Holding AG (CH) 1996-12-18 EP disclosed
WO-1996011978-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-04-25 WO disclosed
EP-0488190-B1 Process for producing powder aggregate particle of high molecular weight polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1996-02-07 EP disclosed
US-5463013-A Transparency, heat resistance, dimensional stability, tracking resistance TEIJIN CHEMICALS, LTD. (JP) 1995-10-31 US disclosed
WO-1995023176-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS CIBA-GEIGY AG (CH) 1995-08-31 WO disclosed
EP-0622393-A2 Modified aromatic polycarbonate resin and modified phenol for preparing it Teijin Chemicals, Ltd. (JP) 1994-11-02 EP disclosed
US-5182363-A Adding poor solvent to solution, pouring into heated water, suspension, distillation, recycling slurry to wet-process pulverizer while further distilling MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1993-01-26 US disclosed
EP-0488190-A1 Process for producing powder aggregate particle of high molecular weight polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-06-03 EP disclosed