Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.33 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | NPY4R | P50391 | 5/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21897483 | 0.88 | FURIN (0.39) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL24831913 | 0.83 | NOD1 (0.41) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL19450715 | 0.81 | DPP7 (0.40) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL23394645 | 0.81 | DPP7 (0.40) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL20385917 | 0.81 | DPP7 (0.40) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL19996650 | 0.80 | FURIN (0.37) | BMP1C3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL22351933 | 0.80 | FURIN (0.37) | BMP1C3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL17758699 | 0.80 | FURIN (0.37) | BMP1C3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL20795891 | 0.80 | FURIN (0.36) | BMP1NMT2NMT1C3AR1SIRT5 | |
| SCHEMBL20159819 | 0.80 | FURIN (0.36) | BMP1NMT2NMT1C3AR1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607996-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3498301-A1 | KIT COMPRISING IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2019-06-19 | — | — | EP | disclosed |
| EP-3134124-B1 | IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017072196-A1 | COMPOSITION FOR THE TREATMENT OF IGF-1R EXPRESSING CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-05-04 | — | — | WO | disclosed |