SCHEMBL21897483

SCHEMBL21897483

CNC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NCO)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 12/20 0.39
▸ NMT2 O60551 1/20 0.33
▸ NMT1 P30419 1/20 0.33
▸ BMP1 P13497 1/20 0.33
▸ C3AR1 Q16581 1/20 0.33
▸ PRSS1 P07477 2/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ MMP1 P03956 1/20 0.32
▸ MMP3 P08254 1/20 0.32
▸ MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22351933 0.90 FURIN (0.37) FURINBMP1C3AR1PRSS1SIRT5
SCHEMBL17758699 0.90 FURIN (0.37) FURINBMP1C3AR1PRSS1SIRT5
SCHEMBL19996650 0.90 FURIN (0.37) FURINBMP1C3AR1PRSS1SIRT5
SCHEMBL23736705 0.89 FURIN (0.36) FURINNMT2NMT1BMP1C3AR1
SCHEMBL20795891 0.89 FURIN (0.36) FURINNMT2NMT1BMP1C3AR1
SCHEMBL20159819 0.89 FURIN (0.36) FURINNMT2NMT1BMP1C3AR1
SCHEMBL18811722 0.88 BMP1 (0.34) FURINNMT2NMT1BMP1C3AR1
SCHEMBL23236822 0.88 BMP1 (0.36) FURINBMP1C3AR1SIRT5SIRT6
SCHEMBL25832984 0.87 FURIN (0.35) FURINNMT2NMT1BMP1C3AR1
SCHEMBL22698746 0.85 FURIN (0.38) FURINNMT2NMT1BMP1C3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 — — US disclosed
US-20230135723-A1 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2023-05-04 — — US disclosed
US-20200121803-A1 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. 2020-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230135723-A1 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES CD99, SLC3A2, CD63 FURIN 4666/4885NMT2 391/4885NMT1 581/4885
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS TPX2, H1-4, MAPT FURIN 1132/4885NMT2 683/4885NMT1 733/4885
US-20200121803-A1 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES CD99, SLC3A2, CD63 FURIN 4666/4885NMT2 391/4885NMT1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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