Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084347 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084307 | 0.92 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17056217 | 0.87 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL18218064 | 0.87 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084348 | 0.87 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084338 | 0.85 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084311 | 0.85 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084345 | 0.84 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084342 | 0.83 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17084344 | 0.83 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165965-B1 | PHOTOSENSITIVE COMPOSITION AND COMPOUND | TOKYO OHKA KOGYO CO LTD (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20170160636-A1 | PHOTOSENSITIVE COMPOSITION AND COMPOUND | TOKYO OHKA KOGYO CO., LTD. (JP) | 2017-06-08 | — | — | US | disclosed |
| EP-3165965-A1 | PHOTOSENSITIVE COMPOSITION AND COMPOUND | Tokyo Ohka Kogyo Co., Ltd. (JP) | 2017-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170160636-A1 | PHOTOSENSITIVE COMPOSITION AND COMPOUND | C1R, CRY1, C1S | NPC1 1861/4885RAB9A 2362/4885SMN1; SMN2 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.