SCHEMBL18813005

SCHEMBL18813005

CC(C)C1CCC(C)(OC(=O)c2ccccc2O)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
TSHR P16473 2/20 0.44
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SCN1A P35498 2/20 0.42
SCN2A Q99250 2/20 0.42
SCN3A Q9NY46 2/20 0.42
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
KDM4E B2RXH2 3/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22283442 0.80 LMNA (0.43) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL27781086 0.80 LMNA (0.51) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL4732801 0.77 SERPINE1 (0.45) LMNATDP1KDM4E
SCHEMBL4651743 0.76 ALDH1A1 (0.52) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL22471699 0.75 SCN1A (0.49) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL22283466 0.75 TSHR (0.46) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL7567142 0.74 OPRL1 (0.38) LMNAALDH1A1CYP1A2SCN1ASCN2A
SCHEMBL7192304 0.73 ALDH1A1 (0.46) LMNATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL4063068 0.72 SCN1A (0.30) SCN1ASCN2ASCN3A
SCHEMBL11692287 0.71 OPRL1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110368180-A Disposable body warmer 大日本除虫菊株式会社 2019-10-25 CN disclosed
EP-3165201-B1 DISPOSABLE BODY WARMER DAINIPPON JOCHUGIKU KK (JP) 2019-04-24 EP disclosed
EP-3165201-A1 DISPOSABLE BODY WARMER DAINIHON JOCHUGIKU CO., LTD. (JP) 2017-05-10 EP disclosed
CN-106456361-A Disposable bosom stove 大日本除虫菊株式会社 2017-02-22 CN disclosed