Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27598190 | 0.88 | APP (0.44) | CNR2APPALOX5GABRA1GABRB2 | |
| Methylamine SCHEMBL28044974 | 0.82 | — | — | |
| Acetic Acid SCHEMBL1662353 | 0.81 | RARA (0.47) | APPALOX5RXRAMEN1POLB | |
| Pyruvate SCHEMBL935493 | 0.77 | RARA (0.45) | APPALOX5RXRAMEN1POLB | |
| Cyanide SCHEMBL28038481 | 0.77 | — | — | |
| SCHEMBL29171599 | 0.77 | APP (0.48) | CNR2APPALOX5GABRA1GABRB2 | |
| Boric Acid SCHEMBL29171600 | 0.77 | APP (0.48) | CNR2APPALOX5GABRA1GABRB2 | |
| Ethylamine SCHEMBL11810037 | 0.76 | ALOX5 (0.50) | CNR2APPALOX5GABRA1GABRB2 | |
| SCHEMBL27475510 | 0.76 | RARA (0.41) | CNR2APPALOX5GABRA1GABRB2 | |
| Methane SCHEMBL28580924 | 0.74 | APP (0.41) | CNR2APPALOX5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113710-A9 | BENZYLISOQUINOLINE UPTAKE PERMEASES AND METHODS OF USING | Willow Biosciences Inc. (CA) | 2020-02-20 | — | — | WO | claimed |
| WO-2019113710-A1 | BENZYLISOQUINOLINE UPTAKE PERMEASES AND METHODS OF USING | SERTURNER CORP. (CA) | 2019-06-20 | — | — | WO | claimed |
| US-20170130250-A1 | Compositions and Methods For Making (S)-Norcoclaurine and (S)-Norlaudanosoline, and Synthesis Intermediates Thereof | HERCULES CAPITAL, INC., AS AGENT | 2017-05-11 | — | — | US | claimed |
| WO-2022150380-A1 | ALKALOID PRODUCING OXIDASES AND CARBOXY-LYASES AND METHODS OF USE | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2022-07-14 | — | — | WO | disclosed |
| US-10662453-B2 | Compositions and methods for making (S)-norcoclaurine and (S)-norlaudanosoline, and synthesis intermediates thereof | Willow Biosciences Inc. (CA) | 2020-05-26 | — | — | US | disclosed |
| WO-2019113710-A9 | BENZYLISOQUINOLINE UPTAKE PERMEASES AND METHODS OF USING | Willow Biosciences Inc. (CA) | 2020-02-20 | — | — | WO | disclosed |
| EP-3158073-B1 | COMPOSITIONS AND METHODS FOR MAKING (S)-NORCOCLAURINE AND (S)-NORLAUDANOSOLINE, AND SYNTHESIS INTERMEDIATES THEREOF | EPIMERON INC (CA) | 2019-10-23 | — | — | EP | disclosed |
| WO-2019113710-A1 | BENZYLISOQUINOLINE UPTAKE PERMEASES AND METHODS OF USING | SERTURNER CORP. (CA) | 2019-06-20 | — | — | WO | disclosed |
| US-10119155-B2 | Compositions and methods for making (S)-norcoclaurine and (S)-norlaudanosoline, and synthesis intermediates thereof | EPIMERON INC. (CA) | 2018-11-06 | — | — | US | disclosed |
| US-20170130250-A1 | Compositions and Methods For Making (S)-Norcoclaurine and (S)-Norlaudanosoline, and Synthesis Intermediates Thereof | HERCULES CAPITAL, INC., AS AGENT | 2017-05-11 | — | — | US | disclosed |