Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347122 | 0.84 | MAPT (0.58) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL17338813 | 0.84 | MAPT (0.58) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL17347077 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL22898545 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL22898531 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL17347078 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL17347214 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL18787397 | 0.82 | ITGB2 (0.44) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 | |
| SCHEMBL22898642 | 0.81 | ITGAL (0.43) | ADRA2AITGB2ICAM1ITGALTSHR | |
| SCHEMBL18816188 | 0.76 | ALDH1A1 (0.52) | ADRA2ACACNA1BAPBA1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121284-A1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121284-A1 | SMALL MOLECULE LFA-1 INHIBITORS | ICAM1, VCAM1, ITGB1 | ADRA2A 1433/4885CACNA1B 414/4885APBA1 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.