Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | NCF1 | P14598 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 10/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031547 | 0.92 | KDM4E (0.79) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29357142 | 0.92 | KDM4E (0.79) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14825073 | 0.91 | MAPT (0.70) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL9438985 | 0.86 | MAPT (0.68) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18844291 | 0.84 | MAPT (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5170654 | 0.84 | MAPT (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4947880 | 0.84 | KDM4E (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18816619 | 0.84 | MAPT (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15533104 | 0.84 | MAPT (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27858514 | 0.84 | KDM4E (0.69) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9855280-B2 | Nanoparticles containing azolium and N-heterocyclic carbene compounds and use thereof | NATIONAL DONG HWA UNIVERSITY (TW) | 2018-01-02 | — | — | US | disclosed |
| US-20170129907-A1 | NANOPARTICLES CONTAINING AZOLIUM AND N-HETEROCYCLIC CARBENE COMPOUNDS AND USE THEREOF | NATIONAL DONG HWA UNIVERSITY (TW) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129907-A1 | NANOPARTICLES CONTAINING AZOLIUM AND N-HETEROCYCLIC CARBENE COMPOUNDS AND USE THEREOF | CCNL2, MUC1, H1-10 | MAPT 2606/4885KDM4E 1524/4885CYP1A2 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.