SCHEMBL18817567

SCHEMBL18817567

CNc1ccc(Oc2ccc(NC(=O)c3ccc(CC(C)=O)cc3C(=O)O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ GFER P55789 1/20 0.49
▸ TDP1 Q9NUW8 3/20 0.48
▸ LMNA P02545 2/20 0.46
▸ PTPN2 P17706 3/20 0.43
▸ PTPN1 P18031 3/20 0.43
▸ POLB P06746 2/20 0.43
▸ PTPN7 P35236 2/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ CRHBP P24387 1/20 0.43
▸ FNTA P49354 1/20 0.43
▸ FNTB P49356 1/20 0.43
▸ CRHR2 Q13324 1/20 0.43
▸ PNLIP P16233 3/20 0.42
▸ KLKB1 P03952 2/20 0.42
▸ NR1H4 Q96RI1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21675646 0.95 MEN1 (0.49) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL18817853 0.90 F3 (0.42) TDP1LMNAALDH1A1NR1H4
SCHEMBL21675701 0.85 F3 (0.42) TDP1LMNAALDH1A1NR1H4
SCHEMBL22681687 0.85 MAPK1 (0.48) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL13878438 0.84 TDP1 (0.59) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL25714253 0.82 SORT1 (0.49) MEN1KMT2AL3MBTL1LMNAALDH1A1
SCHEMBL12539660 0.81 MEN1 (0.53) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL675767 0.79 MEN1 (0.71) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL13866797 0.77 MEN1 (0.52) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL13870130 0.77 MEN1 (0.52) MEN1KMT2AL3MBTL1MAPK1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 — — US disclosed
US-20200148880-A1 PROCESS FOR PREPARING PARTICLES OF AROMATIC POLYMERS, PARTICLES OBTAINABLE BY SAID PROCESS AND THEIR USES SOLVAY SPECIALITY POLYMERS USA, LLC 2020-05-14 — — US disclosed
US-20190241712-A1 POROUS ARTICLE COMPRISING A POLYMER AND AN ADDITIVE, PROCESSES FOR THEIR PREPARATION AND USE THEREOF SOLVAY SPECIALITY POLYMERS USA, LLC 2019-08-08 — — US disclosed
US-10308830-B2 Fluoropolymer composition SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2019-06-04 — — US disclosed
US-20170292022-A1 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-10-12 — — US disclosed
US-20170145242-A1 FLUOROPOLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2017-05-25 — — US disclosed
US-20170121594-A1 Proppant particulates and methods of using such particulates in subterranean applications SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-04 — — US disclosed
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