SCHEMBL18819

SCHEMBL18819

CCOC(=O)c1cc[c]cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.62
CA2 P00918 4/20 0.62
CA12 O43570 3/20 0.62
CA7 P43166 3/20 0.62
CA9 Q16790 3/20 0.62
CA14 Q9ULX7 3/20 0.62
ESR1 P03372 1/20 0.62
ESR2 Q92731 1/20 0.62
LMNA P02545 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
MAOA P21397 1/20 0.60
HPGD P15428 4/20 0.53
HTT P42858 2/20 0.53
TSHR P16473 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HSP90AA1 P07900 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674165 0.98 CA1 (0.60) CA1CA2CA12CA7CA9
SCHEMBL27630213 0.93 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL27756496 0.93 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL11284047 0.87 CA12 (0.49) CA1CA2CA12CA7CA9
SCHEMBL10434776 0.86 CA1 (0.47) CA1CA2CA12CA7CA9
SCHEMBL2261948 0.86 CA12 (0.56) CA1CA2CA12CA7CA9
SCHEMBL28436850 0.85 CA1 (0.47) CA1CA2CA12CA7CA9
SCHEMBL10434629 0.85 CA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL87450 0.84 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL132053 0.84 LMNA (0.67) ESR1LMNACYP1A2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5218 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
CN-118271331-A Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation 赣江中药创新中心 2024-07-02 CN claimed
CN-117986611-A Two isomorphic pentazimene octacarboxylic acid-based hydrogen bond organic framework composite materials with white light emission, and preparation and application thereof 南开大学 2024-05-07 CN claimed
CN-117263760-A Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis 西南医科大学 2023-12-22 CN claimed
US-11834532-B2 Photoinitiators IGH RESINS ITALIA S.R.L. (IT) 2023-12-05 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
WO-2023221952-A1 CYCLIC QUATERNARY AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 宜昌人福药业有限责任公司 2023-11-23 WO claimed
CN-114907282-B Method for synthesizing 4-phenyl alkenyl isoxazole derivative 华南理工大学 2023-08-22 CN claimed
CN-116283534-A Multifunctional chiral eneyne ligand and preparation method and application thereof 中国石油化工股份有限公司 2023-06-23 CN claimed
WO-2023113114-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OVERACTIVE BLADDER 광주과학기술원 2023-06-22 WO claimed
US-4210661-A Synthetic β-lactam compounds, a process for their preparation and compositions containing them BEECHAM GROUP LIMITED (GB) 1980-07-01 US claimed
US-4182897-A ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES TORII & CO., LTD. (JP) 1980-01-08 US claimed
EP-0005911-A1 Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-12-12 EP claimed
US-4118561-A ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY AMERICAN HOME PRODUCTS CORPORATION (US) 1978-10-03 US claimed
US-4085099-A AZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-04-18 US claimed
US-4009206-A CHOLESTEROL LOWERING AGENTS MURAI HIROMU 1977-02-22 US claimed
US-4005092-A Pyrylium dyes having a fused, rigidized nitrogen-containing ring EASTMAN KODAK COMPANY (US) 1977-01-25 US claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed
US-3956307-A FUNGICIDES SCHERING AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-3932415-A Pyrylium dyes having a fused rigidized nitrogen-containing ring EASTMAN KODAK COMPANY (US) 1976-01-13 US claimed