SCHEMBL132053

SCHEMBL132053

CCCOC(=O)c1cc[c]cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.67
ALDH1A1 P00352 6/20 0.65
TSHR P16473 3/20 0.65
TDP1 Q9NUW8 3/20 0.65
ESR1 P03372 2/20 0.65
CHRM1 P11229 1/20 0.65
SLC6A2 P23975 1/20 0.65
KDR P35968 1/20 0.65
STS P08842 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2D6 P10635 1/20 0.51
MAPK1 P28482 1/20 0.51
NR1H2 P55055 1/20 0.51
RNASEL Q05823 1/20 0.51
HPGD P15428 3/20 0.51
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
PDE4D Q08499 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131778 0.89 ESR1 (0.67) LMNAALDH1A1TSHRTDP1ESR1
SCHEMBL11731976 0.88 TDP1 (0.52) LMNAALDH1A1TSHRTDP1ESR1
SCHEMBL1312058 0.87 ALDH1A1 (0.64) LMNAALDH1A1TSHRTDP1ESR1
SCHEMBL6412993 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL710852 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL3221420 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL1310680 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL3225675 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL3262610 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS
SCHEMBL8095886 0.86 ALDH1A1 (0.67) LMNAALDH1A1TSHRESR1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2197552-B1 NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS 4SC AG (DE) 2012-11-21 EP claimed
EP-1832586-A1 Thiazole-piperidine derivatives in treatment of diseases of liver and the pancreas Oridis Biomed Forschungs- und Entwicklungs GmbH (AT) 2007-09-12 EP claimed
EP-0162208-B1 NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1989-11-23 EP claimed
US-4683234-A HYPOTENSIVE AGENTS, ANTI-ANGINA SUNTORY LIMITED (JP) 1987-07-28 US claimed
EP-0162208-A2 Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1985-11-27 EP claimed
CN-117925215-A Electrochromic composition and electrochromic device 泰盈光电股份有限公司 2024-04-26 CN disclosed
US-20240085753-A1 ELECTROCHROMIC COMPOSITION AND ELECTROCHROMIC DEVICE TAI YING OPTRONICS CO., LTD. (TW) 2024-03-14 US disclosed
US-11886119-B2 Material for forming underlayer film, resist underlayer film, method of producing resist underlayer film, and laminate MITSUI CHEMICALS, INC. (JP) 2024-01-30 US disclosed
CN-110709774-B Underlayer film forming material, resist underlayer film, method for producing resist underlayer film, and laminate 三井化学株式会社 2023-12-08 CN disclosed
US-20230384496-A1 OPTICAL MEMBER FOR USE IN DISPLAY DEVICE AND DISPLAY DEVICE INCLUDING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
CN-115521478-B Acidic pH sensing lanthanide MOF material and preparation method and application thereof 广东工业大学 2023-06-16 CN disclosed
US-20230185195-A1 MATERIAL FOR FORMING UNDERLAYER FILM, RESIST UNDERLAYER FILM, METHOD OF PRODUCING RESIST UNDERLAYER FILM, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2023-06-15 US disclosed
EP-0415203-A2 Thiazole dyes of the merocyanine type and a thermal transfer process using these dyes BASF Aktiengesellschaft (DE) 1991-03-06 EP disclosed
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed
EP-0162208-B1 NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1989-11-23 EP disclosed
US-4824834-A TREATING GOUT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-04-25 US disclosed
EP-0273444-A2 Use of carboxamide compounds for the preparation of a medicament for treating hyperlipidemia OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-07-06 EP disclosed
EP-0269859-A2 Pyrazolotriazine compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP disclosed
US-4313874-A DYEING POLYESTERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-02-02 US disclosed
US-4024144-A SULFONIC ACID GROUPS BAYER AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed