Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17750782 | 0.76 | — | — | |
| SCHEMBL18175093 | 0.69 | ADORA2B (0.36) | CYP3A4PMP22LMNAALDH1A1MAPT | |
| SCHEMBL6480956 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL19987789 | 0.61 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL2031094 | 0.57 | CSNK2A2 (0.41) | DAOCYP3A4MAPK1PMP22LMNA | |
| SCHEMBL13870106 | 0.57 | — | — | |
| SCHEMBL633410 | 0.57 | CSNK2A2 (0.41) | EPHX2DAOCYP3A4MAPK1PMP22 | |
| SCHEMBL12263001 | 0.57 | DAO (0.39) | EPHX2DAOCYP3A4MAPK1PMP22 | |
| SCHEMBL924091 | 0.57 | ALDH1A1 (0.55) | DAOCYP3A4MAPK1PMP22LMNA | |
| SCHEMBL19194277 | 0.55 | DAO (0.38) | EPHX2DAOCYP3A4MAPK1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |