Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18795127 | 0.84 | MEN1 (0.38) | HSD11B1CYP2C9KDM4EALDH1A1NPC1 | |
| SCHEMBL17832751 | 0.81 | ALDH1A1 (0.35) | HSD11B1CYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL17832722 | 0.80 | CA12 (0.38) | CYP2C9KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18819688 | 0.79 | MEN1 (0.39) | CYP2C9KDM4EPKMSMN1; SMN2MEN1 | |
| SCHEMBL19439369 | 0.78 | HSD11B1 (0.38) | HSD11B1CYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL17941449 | 0.77 | MEN1 (0.37) | CYP2C9MEN1KMT2APTGS2AGPAT2 | |
| SCHEMBL29679685 | 0.77 | MEN1 (0.37) | CYP2C9MEN1KMT2APTGS2AGPAT2 | |
| SCHEMBL29683444 | 0.77 | CA12 (0.55) | CYP2C9KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20424066 | 0.77 | DHODH (0.37) | HSD11B1CYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL21925086 | 0.76 | KDM4E (0.38) | HSD11B1CYP2C9KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |