Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820266 | 0.98 | GAA (0.41) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL10896436 | 0.94 | MAPT (0.43) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL11651390 | 0.94 | MAPT (0.43) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL7335395 | 0.84 | MAPT (0.37) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL16886019 | 0.79 | NISCH (0.38) | GAAMAPTL3MBTL1NPC1HPGD | |
| SCHEMBL7332315 | 0.79 | NISCH (0.38) | GAAMAPTL3MBTL1NPC1HPGD | |
| SCHEMBL7332320 | 0.79 | NISCH (0.38) | GAAMAPTL3MBTL1NPC1HPGD | |
| SCHEMBL3224077 | 0.77 | ATM (0.48) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL3224073 | 0.77 | ATM (0.48) | GAAMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL9059860 | 0.76 | SIGMAR1 (0.39) | CYP1A2MAPTNISCHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368643-B1 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | CHEVRON ORONITE CO (US) | 2019-11-20 | — | — | EP | disclosed |
| US-9752092-B2 | Lubricating oil compositions containing amidine antioxidants | CHEVRON ORONITE COMPANY LLC (US) | 2017-09-05 | — | — | US | disclosed |
| US-20170121625-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | CHEVRON ORONITE COMPANY LLC | 2017-05-04 | — | — | US | disclosed |