Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332320 | 1.00 | NISCH (0.38) | NISCHALDH1A1GAAGFERHPGD | |
| SCHEMBL7332315 | 1.00 | NISCH (0.38) | NISCHALDH1A1GAAGFERHPGD | |
| SCHEMBL18820266 | 0.81 | GAA (0.41) | NISCHALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7333677 | 0.81 | HSD17B10 (0.38) | ALDH1A1GAAMAPTHTR3EHTR3B | |
| SCHEMBL18820390 | 0.79 | GAA (0.42) | NISCHALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL16892098 | 0.78 | APOBEC3A (0.42) | ALDH1A1HPGDTDP1MAPTLMNA | |
| SCHEMBL18820353 | 0.78 | NISCH (0.41) | NISCHALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11245810 | 0.77 | GAA (0.41) | GAATDP1RAB9AMAPTLMNA | |
| SCHEMBL11245811 | 0.77 | GAA (0.41) | GAATDP1RAB9AMAPTLMNA | |
| SCHEMBL18819704 | 0.76 | NISCH (0.42) | NISCHALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611276-B2 | Imidazo bicyclic iminium compounds as antitumor agents | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150191489-A1 | IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191489-A1 | IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS | GLI1, SHH, SMO | NISCH 1146/4885ALDH1A1 1015/4885GAA 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.