Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032694 | 0.86 | NPC1 (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL10585877 | 0.79 | ALDH1A1 (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL10828887 | 0.76 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2TP53CYP3A4 | |
| SCHEMBL6653492 | 0.73 | PTPN1 (0.33) | — | |
| SCHEMBL9019053 | 0.70 | NPC1 (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9150766 | 0.69 | BACE1 (0.49) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL941733 | 0.67 | ALDH1A1 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7225542 | 0.66 | ADORA2A (0.38) | PTPRC | |
| SCHEMBL9811013 | 0.66 | PTPN1 (0.37) | — | |
| SCHEMBL28679867 | 0.66 | MAOA (0.40) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8253583-A | — | — | None | — | — | JP | disclosed |
| JP-H08253583-A | POLYIMIDE RESIN MOLDING | FURUKAWA ELECTRIC CO LTD:THE | 1996-10-01 | — | — | JP | disclosed |