SCHEMBL18822412

SCHEMBL18822412

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nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 16/20 0.39
▸ DPP8 Q6V1X1 10/20 0.39
▸ DPP9 Q86TI2 9/20 0.39
▸ DPP7 Q9UHL4 9/20 0.35
▸ FAP Q12884 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8751922 0.86 DPP4 (0.42) DPP4DPP8DPP9DPP7FAP
SCHEMBL22890984 0.86 DPP4 (0.42) DPP4DPP8DPP9DPP7FAP
SCHEMBL21985751 0.83 DPP4 (0.40) DPP4DPP8DPP9DPP7
SCHEMBL1982494 0.81 LMNA (0.32) —
SCHEMBL21105595 0.80 DPP4 (0.43) DPP4DPP8DPP9DPP7
SCHEMBL7779225 0.80 DPP4 (0.43) DPP4DPP8DPP9DPP7
SCHEMBL7779224 0.80 DPP4 (0.43) DPP4DPP8DPP9DPP7
SCHEMBL3194064 0.79 DPP4 (0.37) DPP4DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL16007456 0.79 DPP4 (0.42) DPP4DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL11122949 0.79 DPP4 (0.42) DPP4DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10414800-B2 Methods for producing a depsipeptide NOVOBIOTIC PHARMACEUTICALS, LLC (US) 2019-09-17 — — US disclosed
US-20170121372-A1 NOVEL DEPSIPEPTIDE AND USES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121372-A1 NOVEL DEPSIPEPTIDE AND USES THEREOF VIP, DPP7, DNPEP DPP4 8/4885DPP8 6/4885DPP9 10/4885
US-10414800-B2 Methods for producing a depsipeptide VIP, DNPEP, PSAP DPP4 14/4885DPP8 12/4885DPP9 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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