Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19201869 | 0.82 | EPHX1 (0.33) | — | |
| SCHEMBL9735358 | 0.80 | APEX1 (0.36) | APEX1GABRR1CYP1A2 | |
| SCHEMBL7845774 | 0.79 | GABRR1 (0.46) | APEX1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL9240028 | 0.77 | OR51E2 (0.37) | — | |
| SCHEMBL7397212 | 0.77 | OR51E2 (0.37) | — | |
| SCHEMBL20763602 | 0.75 | ARG1 (0.48) | — | |
| SCHEMBL18822325 | 0.75 | ARG1 (0.48) | — | |
| SCHEMBL17530133 | 0.75 | GABRR1 (0.42) | APEX1GABRR1CYP1A2FOLH1NAALAD2 | |
| SCHEMBL19136510 | 0.75 | MTNR1A (0.33) | — | |
| SCHEMBL15346472 | 0.74 | GABRR1 (0.38) | APEX1GABRR1CYP1A2FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075505-A2 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |