Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1882782 | 0.94 | PDE5A (0.36) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL12636803 | 0.91 | PDE4B (0.34) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL1878729 | 0.90 | LMNA (0.35) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL1878669 | 0.88 | PDE5A (0.42) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL1880157 | 0.88 | LMNA (0.36) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL14570910 | 0.88 | SYK (0.32) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL14570909 | 0.86 | ALDH1A1 (0.32) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL1961670 | 0.85 | CYP1A2 (0.34) | SMN1; SMN2LMNAALDH1A1GAAHTT | |
| SCHEMBL1880294 | 0.85 | LMNA (0.37) | SMN1; SMN2RAB9ALMNAALDH1A1GAA | |
| SCHEMBL1882274 | 0.84 | PDE4B (0.42) | SMN1; SMN2RAB9ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939467-B2 | Controlling broadleaf plants and weeds and grasses | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | claimed |
| EP-2137159-A1 | 4-(3-AMINOBENZOYL)-1-ETHYLPYRAZOLE AND THE USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | claimed |
| WO-2008125212-A1 | 4-(3-AMINOBENZOYL)-1-ETHYLPYRAZOLE AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | claimed |
| US-20080254991-A1 | 4-(3-Aminobenzoyl)-1-ethylpyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | US | claimed |
| US-7939467-B2 | Controlling broadleaf plants and weeds and grasses | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| EP-2137159-A1 | 4-(3-AMINOBENZOYL)-1-ETHYLPYRAZOLE AND THE USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125212-A1 | 4-(3-AMINOBENZOYL)-1-ETHYLPYRAZOLE AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| US-20080254991-A1 | 4-(3-Aminobenzoyl)-1-ethylpyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1980554-A1 | 4-(3-aminobenzoyl)-1-ethyl pyrazoles and their application as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080254991-A1 | 4-(3-Aminobenzoyl)-1-ethylpyrazoles and their use as herbicides | DDT, ABAT, TH | SMN1; SMN2 4488/4885RAB9A 1203/4885LMNA 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.