SCHEMBL18823045

SCHEMBL18823045

CC(F)(F)CC(O)COC(=O)c1cc(C(=O)OCCC(O)C(C)(F)F)cc(S(=O)(=O)O)c1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 17/20 0.34
ADRB1 P08588 17/20 0.34
ADRB3 P13945 17/20 0.34
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879778 0.90 LCK (0.38) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL18823046 0.78 LCK (0.33) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL18823095 0.78 LCK (0.38) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL18823105 0.78
SCHEMBL17879776 0.77 LCK (0.35) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL17879747 0.74 LCK (0.43) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL17883745 0.72 SERPINE1 (0.33) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL6293055 0.71 PKM (0.55) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL6856008 0.71 PKM (0.55) KDM4EALDH1A1GAAPKMKMT2A
SCHEMBL13520460 0.71 LCK (0.46) ADRB2ADRB1ADRB3ALDH1A1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10481495-B2 Topcoat compositions containing fluorinated thermal acid generators ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-11-19 US disclosed
US-20190243246-A1 TOPCOAT COMPOSITIONS CONTAINING FLUORINATED THERMAL ACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-08 US disclosed
US-10007179-B2 Thermal acid generators and photoresist pattern trimming compositions and methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-06-26 US disclosed
US-20180118968-A1 TOPCOAT COMPOSITIONS CONTAINING FLUORINATED THERMAL ACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-05-03 US disclosed
US-20170123314-A1 THERMAL ACID GENERATORS AND PHOTORESIST PATTERN TRIMMING COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10007179-B2 Thermal acid generators and photoresist pattern trimming compositions and methods ADH1A, PUF60, PARG ADRB2 4619/4885ADRB1 4664/4885ADRB3 4635/4885
US-20170123314-A1 THERMAL ACID GENERATORS AND PHOTORESIST PATTERN TRIMMING COMPOSITIONS AND METHODS ADH1A, PUF60, PARG ADRB2 4619/4885ADRB1 4664/4885ADRB3 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.