Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 8/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 8/20 | 0.56 |
| ▸ | TOP2A | P11388 | 6/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bryodulcosigenin SCHEMBL18805155 | 0.88 | PRKAG1 (0.71) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| SCHEMBL18823677 | 0.84 | PRKAG1 (0.80) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL18823922 | 0.82 | PRKAG1 (0.48) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| SCHEMBL18823332 | 0.82 | PRKAG1 (0.40) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| SCHEMBL18805316 | 0.81 | PRKAG1 (0.60) | PRKAG1PRKAA2PRKAB1 | |
| Cabenoside D SCHEMBL18805159 | 0.79 | PRKAG1 (0.49) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| Cabenoside D SCHEMBL30340049 | 0.79 | PRKAG1 (0.49) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| SCHEMBL18823351 | 0.79 | TOP2A (0.41) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B | |
| SCHEMBL18818128 | 0.78 | PRKAG1 (0.56) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL18823457 | 0.78 | PRKAG1 (0.36) | PRKAG1PRKAA2PRKAB1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075257-A2 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. (US) | 2017-05-04 | — | — | WO | disclosed |