Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CRYAB | P02511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823626 | 0.79 | PRKAG1 (0.56) | TOP2ATOP2BACHEPRKAG1PRKAA2 | |
| Bryodulcosigenin SCHEMBL18805155 | 0.70 | PRKAG1 (0.71) | TOP2ATOP2BACHEPRKAG1PRKAA2 | |
| SCHEMBL18823677 | 0.67 | PRKAG1 (0.80) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL23781798 | 0.67 | EBP (0.43) | FNTAFNTB | |
| SCHEMBL5824299 | 0.67 | HSD11B1 (0.61) | TOP2ATOP2BACHEHSD11B1HSD11B2 | |
| SCHEMBL18823922 | 0.66 | PRKAG1 (0.48) | TOP2ATOP2BACHEPRKAG1PRKAA2 | |
| SCHEMBL17431782 | 0.66 | HSD11B1 (0.55) | TOP2ATOP2BACHEHSD11B1HSD11B2 | |
| SCHEMBL17428529 | 0.66 | HSD11B1 (0.44) | TOP2ATOP2BACHEHSD11B1HSD11B2 | |
| SCHEMBL13642319 | 0.63 | HSD11B1 (0.62) | TOP2ATOP2BACHEHSD11B1HSD11B2 | |
| 3Beta,24,25-Trihydroxycycloartane SCHEMBL3306653 | 0.63 | HSD11B1 (0.76) | TOP2ATOP2BACHEHSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075257-A2 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. (US) | 2017-05-04 | — | — | WO | disclosed |