Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823965 | 0.88 | THRB (0.44) | THRBMEN1KMT2ATSHRPOLB | |
| SCHEMBL20505202 | 0.85 | THRB (0.50) | THRBMEN1KMT2ATSHRPOLB | |
| SCHEMBL15759032 | 0.85 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL22460823 | 0.84 | THRB (0.44) | THRBMEN1KMT2ATSHRPOLB | |
| SCHEMBL12912817 | 0.84 | TSHR (0.57) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL18823962 | 0.83 | THRB (0.42) | THRBMEN1KMT2ATSHRPOLB | |
| SCHEMBL27261784 | 0.82 | THRB (0.51) | THRBMEN1KMT2ATSHRPOLB | |
| SCHEMBL2600105 | 0.81 | TSHR (0.54) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16744077 | 0.80 | THRB (0.61) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL124287 | 0.80 | THRB (0.61) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121279-A1 | LIPOCATIONIC DENDRIMERS AND USES THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121279-A1 | LIPOCATIONIC DENDRIMERS AND USES THEREOF | LIPA, LIPC, TLR9 | THRB 3413/4885MEN1 2361/4885KMT2A 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.