Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18824379 | 1.00 | TACR1 (0.44) | TACR1EPHX1NPC1RAB9AHDAC8 | |
| SCHEMBL18824395 | 0.77 | HDAC4 (0.52) | HDAC8HDAC6HDAC1HDAC2 | |
| SCHEMBL18824398 | 0.72 | HDAC8 (0.52) | HDAC8HDAC6HDAC1HDAC2GAA | |
| SCHEMBL18824397 | 0.72 | HDAC8 (0.52) | HDAC8HDAC6HDAC1HDAC2GAA | |
| SCHEMBL14762858 | 0.70 | TACR1 (0.56) | TACR1NPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL14858632 | 0.70 | TACR1 (0.56) | TACR1NPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL14762860 | 0.70 | TACR1 (0.56) | TACR1NPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL17205685 | 0.68 | F11 (0.53) | TACR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12525246 | 0.67 | ALDH1A1 (0.56) | TACR1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17377396 | 0.67 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3370525-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017076740-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2017-05-11 | — | — | WO | disclosed |