SCHEMBL18826293

SCHEMBL18826293

C=C(C)C(=O)OC1(c2cc3ccc2o3)c2ccccc2Sc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 2/20 0.32
ELANE P08246 1/20 0.32
BCHE P06276 3/20 0.30
MEN1 O00255 2/20 0.30
MAPT P10636 2/20 0.30
KMT2A Q03164 2/20 0.30
CYBB P04839 1/20 0.30
APP P05067 1/20 0.30
GAA P10253 1/20 0.30
ALOX15 P16050 1/20 0.30
SNCA P37840 1/20 0.30
NOX3 Q9HBY0 1/20 0.30
NOX4 Q9NPH5 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19771489 0.88 ALDH1A1 (0.36) ELANEMEN1MAPTKMT2AUSP2
SCHEMBL20306521 0.87 MAPT (0.35) ELANEMEN1MAPTKMT2AUSP2
SCHEMBL20306519 0.85 ALDH1A1 (0.36) ELANEMEN1MAPTKMT2AUSP2
SCHEMBL19335516 0.80 DHFR (0.32) MEN1MAPTKMT2AUSP2ALDH1A1
SCHEMBL9610564 0.80 ELANE (0.32) NOX1ELANE
SCHEMBL9610548 0.78 ELANE (0.39) NOX1ELANEBCHEMEN1MAPT
SCHEMBL9610589 0.77 ALDH1A1 (0.35) NOX1ELANEMEN1MAPTKMT2A
SCHEMBL9610553 0.76 ELANE (0.39) NOX1ELANEBCHEMEN1MAPT
SCHEMBL19771568 0.76
SCHEMBL9610569 0.74 ELANE (0.33) NOX1ELANEMAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007178-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-9645498-B2 Developer and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-09 US disclosed