Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318856 | 0.89 | MGAM (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2549107 | 0.88 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL17469115 | 0.86 | NAAA (0.35) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4632405 | 0.84 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6067665 | 0.83 | L3MBTL1 (0.49) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7952798 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5001444 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5081305 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10289814 | 0.80 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18120823 | 0.80 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931708-B1 | CYCLOPROPYLBORONIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF | DIVERCHIM (FR) | 2017-05-10 | — | — | EP | disclosed |