SCHEMBL188286

SCHEMBL188286

CO[Si](COCC1CO1)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 8/20 0.42
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 4/20 0.33
CYP3A4 P08684 2/20 0.33
GLA P06280 1/20 0.32
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
HIF1A Q16665 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARG P37231 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5597327 0.89 SMN1; SMN2 (0.42) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL13260278 0.87 SMN1; SMN2 (0.43) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266266 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL1868365 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL230991 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266721 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL12928030 0.79 TSHR (0.52) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
Water SCHEMBL28215215 0.79 SMN1; SMN2 (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL188031 0.79 SMN1; SMN2 (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL187859 0.79 TSHR (0.54) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
EP-4540300-A1 HIGH HARDNESS, LOW VISCOSITY UV CURABLE POTTING ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2025-04-23 EP claimed
EP-3593367-B1 SOLID ELECTROLYTIC CAPACITOR ASSEMBLY KYOCERA AVX COMPONENTS CORP (US) 2024-11-20 EP claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
WO-2023241881-A1 HIGH HARDNESS, LOW VISCOSITY UV CURABLE POTTING ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2023-12-21 WO claimed
CN-116075559-B Optical article with low interference fringe and coating agent composition thereof 日本精化株式会社 2023-12-05 CN claimed
US-20230348750-A1 LOW INTERFERENCE FRINGE OPTICAL ARTICLE AND COATING AGENT COMPOSITION THEREOF NIPPON FINE CHEMICAL CO., LTD. (JP) 2023-11-02 US claimed
US-11756742-B1 Tantalum capacitor with improved leakage current stability at high temperatures KYOCERA AVX Components Corporation (US) 2023-09-12 US claimed
CN-116004149-A Curable transparent resin composition and various articles derived therefrom 韩国太阳油墨股份公司 2023-04-25 CN claimed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
WO-2001089820-A2 COMPOSITIONS AND METHODS FOR COATING A SUBSTRATE TRITON SYSTEMS, INC. (US) 2001-11-29 WO claimed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US claimed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP claimed
EP-0682061-B1 MOLDING WITH HARD-COATING LAYER AND PROCESS FOR PRODUCING THE SAME NIPPON ZEON CO (JP) 2001-09-05 EP claimed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
US-5725960-A Molded articles having hard coat layer and method for producing same NIPPON ZEON CO., LTD. (JP) 1998-03-10 US claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
EP-0682061-A1 MOLDING WITH HARD-COATING LAYER AND PROCESS FOR PRODUCING THE SAME NIPPON ZEON CO., LTD. (JP) 1995-11-15 EP claimed
EP-0620255-A1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD. (KR) 1994-10-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118766-A1 Silicon containing coating compositions and uses thereof ITGA8, SMCHD1, GCN1 TSHR 957/4885MAPK1 4106/4885SMN1; SMN2 259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.