SCHEMBL230991

SCHEMBL230991

CO[Si](C)(COCC1CO1)OC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 8/20 0.42
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 4/20 0.33
CYP3A4 P08684 2/20 0.33
GLA P06280 1/20 0.32
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
HIF1A Q16665 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARG P37231 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5266266 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL1868365 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266721 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL188286 0.83 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL12928030 0.79 TSHR (0.52) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL229581 0.79 SMN1; SMN2 (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL233473 0.79 TSHR (0.54) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL23521500 0.78 SMN1; SMN2 (0.46) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5270708 0.78 SMN1; SMN2 (0.46) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL27618829 0.77 TSHR (0.50) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
US-20230348750-A1 LOW INTERFERENCE FRINGE OPTICAL ARTICLE AND COATING AGENT COMPOSITION THEREOF NIPPON FINE CHEMICAL CO., LTD. (JP) 2023-11-02 US claimed
CN-112831206-A Inorganic oxide dispersion with controllable water content and preparation method thereof 凯斯科技股份有限公司 2021-05-25 CN claimed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US claimed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US claimed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP claimed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
US-6391433-B1 None US disclosed
US-20260133349-A1 EYEGLASS LENS AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2026-05-14 US disclosed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US disclosed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-4590117-A HARDENED LAYERS OF OXIDES OF ALUMINUM, TITANIUM AND/OR ZIRCONIUM AND A POLYSILOXANE; DYEABILITY; LENS TORAY INDUSTRIES, INC. (JP) 1986-05-20 US disclosed
US-4522966-A CURABLE MIXTURE OF GLYCIDYL-CONTAINING ACRYLIC POLYMER, A POLYOXYALKYLENE GLYCOL AND CATALYST NIPPON SHEET GLASS CO., LTD. (JP) 1985-06-11 US disclosed
EP-0119331-A1 Transparent material having antireflective coating TORAY INDUSTRIES, INC. (JP) 1984-09-26 EP disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed
US-4394177-A Coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 TSHR 4084/4885MAPK1 2597/4885SMN1; SMN2 1964/4885
US-20260118766-A1 Silicon containing coating compositions and uses thereof ITGA8, SMCHD1, GCN1 TSHR 957/4885MAPK1 4106/4885SMN1; SMN2 259/4885
US-20260133349-A1 EYEGLASS LENS AND EYEGLASSES TLL1, GLUL, POT1 TSHR 753/4885MAPK1 2574/4885SMN1; SMN2 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.