Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15585678 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL525493 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL9977456 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL204043 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL17772168 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL6469 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL1806573 | 0.89 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL240387 | 0.79 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL240388 | 0.79 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL16729249 | 0.78 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640719-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-05-10 | — | — | EP | disclosed |