Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FER | P16591 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594087 | 0.72 | NPC1 (0.41) | — | |
| SCHEMBL11802702 | 0.68 | BRD4 (0.44) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL7623449 | 0.67 | — | — | |
| SCHEMBL14042850 | 0.66 | MAOA (0.31) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL2294908 | 0.65 | BCHE (0.43) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL6006940 | 0.65 | MEN1 (0.39) | — | |
| SCHEMBL13354600 | 0.64 | NPC1 (0.55) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL16187233 | 0.64 | — | — | |
| SCHEMBL1130729 | 0.63 | NOS2 (0.41) | PDGFRAFERLTKCDK8ACVR1 | |
| SCHEMBL168935 | 0.63 | PDGFRA (0.52) | PDGFRAFERLTKCDK8ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872512-B1 | BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2017-05-10 | — | — | EP | disclosed |