SCHEMBL1883155

SCHEMBL1883155

Fc1[c]c(C(F)(F)F)cnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4923645 0.65
SCHEMBL4928193 0.65
SCHEMBL148397 0.63 ALDH1A1 (0.31)
SCHEMBL407461 0.62 KDM5A (0.30)
SCHEMBL4921302 0.60
SCHEMBL4926578 0.60
SCHEMBL2888795 0.59 PIK3CD (0.32)
SCHEMBL21981227 0.58 CYP11B2 (0.33)
SCHEMBL4917124 0.58 BAZ2B (0.32)
SCHEMBL4928589 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947679-B2 Fungicides SYNGENTA CROP PROTECTION, INC. (US) 2011-05-24 US disclosed
US-20100093738-A1 Fungicidal Compounds and Fungicidal Compositions BASF SE (DE) 2010-04-15 US disclosed
EP-2097412-A2 FUNGICIDAL N-HETEROARYL-CONDENSED PYRIDINE DERIVATIVES AND FUNGICIDAL COMPOSITIONS BASF SE (DE) 2009-09-09 EP disclosed
US-20090069333-A1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-03-12 US disclosed
US-20080287472-A1 Fungicides SYNGENTA CROP PROTECTION, INC. (US) 2008-11-20 US disclosed
US-20080280766-A1 Pyridopyrazines for Combating Phytopathogenic Fungi SYNGENTA CROP PROTECTION, INC. (US) 2008-11-13 US disclosed
US-7410967-B2 Pyridodiazines as plant fungicides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-12 US disclosed
WO-2008040820-A2 FUNGICIDAL N-HETEROARYL-CONDENSED PYRIDINE DERIVATIVES AND FUNGICIDAL COMPOSITIONS BASF SE (DE) 2008-04-10 WO disclosed
EP-1575949-B1 FUNGICIDES SYNGENTA LTD (GB) 2008-04-02 EP disclosed
EP-1575956-B1 FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES SYNGENTA LTD (GB) 2007-03-28 EP disclosed
US-20060069089-A1 Fungicides SYNGENTA CROP PROTECTION, INC. 2006-03-30 US disclosed
WO-2005123733-A1 PYRIDOPYRAZINES FOR COMBATTING PHYTOPATHOGENIC FUNGI SYNGENTA PARTICIPATIONS AG (CH) 2005-12-29 WO disclosed
EP-1585746-A2 NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES Syngenta Limited (GB) 2005-10-19 EP disclosed
EP-1575948-A1 PYRIDODIAZINES AS PLANT FUNGICIDES Syngenta Limited (GB) 2005-09-21 EP disclosed
EP-1575956-A1 FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES Syngenta Limited (GB) 2005-09-21 EP disclosed
EP-1575949-A1 FUNGICIDES Syngenta Limited (GB) 2005-09-21 EP disclosed
WO-2004056826-A1 FUNGICIDES SYNGENTA LIMITED (GB) 2004-07-08 WO disclosed
WO-2004056825-A1 PYRIDODIAZINES AS PLANT FUNGICIDES SYNGENTA LIMITED (GB) 2004-07-08 WO disclosed
WO-2004056829-A1 FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES SYNGENTA LIMITED (GB) 2004-07-08 WO disclosed
WO-2004056824-A2 NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA LIMITED (GB) 2004-07-08 WO disclosed