Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 13/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686643 | 0.83 | MRGPRX4 (0.41) | MRGPRX4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19646121 | 0.80 | MRGPRX4 (0.46) | MRGPRX4MET | |
| SCHEMBL18831532 | 0.75 | MRGPRX4 (0.64) | MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18831671 | 0.74 | MRGPRX4 (0.43) | MRGPRX4 | |
| SCHEMBL18831596 | 0.74 | MRGPRX4 (0.43) | MRGPRX4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18831652 | 0.73 | MRGPRX4 (0.38) | MRGPRX4METNPC1MAPTRAB9A | |
| SCHEMBL20686856 | 0.72 | SMN1; SMN2 (0.40) | MRGPRX4METNPC1MAPTRAB9A | |
| SCHEMBL21317952 | 0.70 | CD274 (0.36) | MRGPRX4CD274 | |
| SCHEMBL18831579 | 0.70 | MRGPRX4 (0.40) | MRGPRX4 | |
| SCHEMBL18831573 | 0.70 | MET (0.37) | MRGPRX4METLTB4RLTB4R2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |