Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 14/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21317952 | 0.88 | CD274 (0.36) | MRGPRX4 | |
| SCHEMBL18831570 | 0.87 | NPC1 (0.35) | MRGPRX4ALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL18831573 | 0.87 | MET (0.37) | MRGPRX4 | |
| SCHEMBL18871219 | 0.85 | L3MBTL1 (0.39) | MRGPRX4ALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL18831440 | 0.85 | MRGPRX4 (0.38) | MRGPRX4 | |
| SCHEMBL18871330 | 0.84 | MRGPRX4 (0.39) | MRGPRX4ALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL18831388 | 0.84 | MRGPRX4 (0.33) | MRGPRX4ALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL18831744 | 0.83 | MRGPRX4 (0.41) | MRGPRX4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18831262 | 0.82 | MRGPRX4 (0.35) | MRGPRX4 | |
| SCHEMBL18831638 | 0.82 | MRGPRX4 (0.39) | MRGPRX4SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940012-B1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |