Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16920926 | 0.90 | MRGPRX4 (0.55) | MRGPRX4LMNAAPEX1NPC1MITF | |
| SCHEMBL18831494 | 0.89 | MRGPRX4 (0.47) | MRGPRX4APEX1PTGER1 | |
| SCHEMBL18831484 | 0.87 | MRGPRX4 (0.50) | MRGPRX4APEX1 | |
| SCHEMBL18831470 | 0.86 | MRGPRX4 (0.54) | MRGPRX4LMNANPC1MITFRAB9A | |
| SCHEMBL18831634 | 0.86 | MRGPRX4 (0.53) | MRGPRX4APEX1 | |
| SCHEMBL18831597 | 0.84 | MRGPRX4 (0.50) | MRGPRX4 | |
| SCHEMBL18831409 | 0.84 | MRGPRX4 (0.47) | MRGPRX4APEX1 | |
| SCHEMBL18831781 | 0.83 | ALDH1A1 (0.45) | MRGPRX4ESR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16920927 | 0.81 | MRGPRX4 (0.57) | MRGPRX4LMNANPC1MITFRAB9A | |
| SCHEMBL16920924 | 0.79 | MRGPRX4 (0.56) | MRGPRX4LMNAAPEX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828389-B2 | Tetrazolinone compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-28 | — | — | US | disclosed |
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |