Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831464 | 0.88 | MRGPRX4 (0.40) | ALDH1A1MRGPRX4CALM1HSD17B10MEN1 | |
| SCHEMBL16920891 | 0.88 | MRGPRX4 (0.47) | ALDH1A1MRGPRX4HSD17B10NPC1USP2 | |
| SCHEMBL18831507 | 0.86 | SLC22A12 (0.42) | MRGPRX4RAB9AMAPT | |
| SCHEMBL19646170 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MRGPRX4CALM1HSD17B10NPC1 | |
| SCHEMBL18831608 | 0.84 | MRGPRX4 (0.39) | MRGPRX4 | |
| SCHEMBL18831787 | 0.83 | MRGPRX4 (0.46) | ESR1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18831571 | 0.82 | MET (0.48) | ALDH1A1MRGPRX4SMN1; SMN2MAPTMEN1 | |
| SCHEMBL18831618 | 0.82 | FFAR4 (0.40) | MRGPRX4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL18831616 | 0.81 | ESR1 (0.38) | ALDH1A1ESR1MRGPRX4CALM1HSD17B10 | |
| SCHEMBL3717467 | 0.81 | ESR1 (0.54) | ALDH1A1ESR1CALM1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828389-B2 | Tetrazolinone compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-28 | — | — | US | disclosed |
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |