Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.72 |
| ▸ | EGFR | P00533 | 7/20 | 0.61 |
| ▸ | INSR | P06213 | 3/20 | 0.55 |
| ▸ | IGF1R | P08069 | 2/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831913 | 0.96 | ALK (0.72) | ALKEGFRINSRIGF1RAXL | |
| SCHEMBL18831884 | 0.91 | ALK (0.72) | ALKEGFRINSRIGF1RAXL | |
| SCHEMBL18831885 | 0.88 | EGFR (0.62) | ALKEGFRINSRIGF1RAXL | |
| SCHEMBL17411098 | 0.84 | ALK (1.00) | ALKEGFRINSRIGF1R | |
| SCHEMBL25299463 | 0.83 | ALK (0.72) | ALKEGFR | |
| SCHEMBL29059674 | 0.82 | ALK (0.74) | ALKEGFRINSRIGF1R | |
| SCHEMBL25872148 | 0.82 | ALK (0.73) | ALKEGFRINSRIGF1R | |
| SCHEMBL18831904 | 0.82 | ALK (0.72) | ALKEGFRINSRIGF1R | |
| SCHEMBL18831886 | 0.82 | ALK (0.72) | ALKEGFRINSRIGF1R | |
| SCHEMBL25308115 | 0.81 | ALK (0.71) | ALKEGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165530-A1 | SPIROCYCLIC ARYL PHOSPHORUS OXIDE AND ARYL PHOSPHORUS SULFIDE | Qilu Pharmaceutical Co., Ltd (CN) | 2017-05-10 | — | — | EP | disclosed |