Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 19/20 | 0.62 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533410 | 0.81 | PDE5A (0.46) | PTK2 | |
| SCHEMBL31344585 | 0.76 | XDH (0.52) | — | |
| SCHEMBL20887600 | 0.75 | TTK (0.66) | PTK2MAP4K1 | |
| SCHEMBL31344557 | 0.74 | PTK2 (0.66) | PTK2 | |
| SCHEMBL29426202 | 0.74 | TTBK1 (0.58) | — | |
| SCHEMBL13213027 | 0.74 | TTBK1 (0.58) | — | |
| SCHEMBL11916362 | 0.74 | CDK7 (0.60) | PTK2MAP4K1 | |
| SCHEMBL29400320 | 0.74 | CDK7 (0.60) | PTK2MAP4K1 | |
| SCHEMBL30503695 | 0.73 | CDK7 (0.48) | PTK2MAP4K1 | |
| SCHEMBL14240767 | 0.73 | CDK7 (0.48) | PTK2MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154091-A1 | SUBSTITUTED DIAMINOPYRIMIDINE COMPOUND | 深圳市塔吉瑞生物医药有限公司 | 2019-08-15 | — | — | WO | disclosed |
| EP-3165530-A1 | SPIROCYCLIC ARYL PHOSPHORUS OXIDE AND ARYL PHOSPHORUS SULFIDE | Qilu Pharmaceutical Co., Ltd (CN) | 2017-05-10 | — | — | EP | disclosed |