SCHEMBL18832149

SCHEMBL18832149

CCCCCCSCCC(O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.66
FFAR1 O14842 1/20 0.66
MAPT P10636 2/20 0.53
GMNN O75496 1/20 0.53
TP53 P04637 1/20 0.53
POLB P06746 1/20 0.53
THRB P10828 1/20 0.53
CYP2C9 P11712 1/20 0.53
BLM P54132 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CES2 O00748 3/20 0.48
S1PR2 O95136 1/20 0.46
S1PR4 O95977 1/20 0.46
S1PR1 P21453 1/20 0.46
S1PR3 Q99500 1/20 0.46
BHMT Q93088 1/20 0.45
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18832145 1.00 GPR84 (0.66) GPR84FFAR1MAPTGMNNTP53
SCHEMBL18832138 1.00 GPR84 (0.66) GPR84FFAR1MAPTGMNNTP53
SCHEMBL18832143 0.98 GPR84 (0.62) GPR84FFAR1MAPTGMNNTP53
SCHEMBL11550378 0.93 GPR84 (0.78) GPR84FFAR1MAPTGMNNTP53
SCHEMBL4951710 0.92 GPR84 (0.59) GPR84FFAR1MAPTGMNNTP53
SCHEMBL723123 0.84 GPR84 (0.52) GPR84FFAR1BHMT
SCHEMBL722785 0.83 GPR84 (0.62) GPR84FFAR1MAPTGMNNTP53
SCHEMBL9937927 0.81 GPR84 (0.59) GPR84FFAR1MAPTGMNNTP53
SCHEMBL7377715 0.81 GPR84 (0.53) GPR84FFAR1MAPTGMNNTP53
SCHEMBL18832137 0.80 BHMT (0.70) MAPTGMNNTP53POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795511-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2020-02-11 CN disclosed
CN-106661571-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2019-12-20 CN disclosed
EP-3168301-B1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP disclosed
US-10364448-B2 Method for producing L-α-amino acid compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-30 US disclosed
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-16 US disclosed
US-20170191097-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-06 US disclosed
US-20170159029-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
EP-3168301-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed
EP-3168302-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USES FOR BOTH Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof DAO, PNPO, HAO1 GPR84 4093/4885FFAR1 2509/4885MAPT 4400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.