Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262945 | 0.88 | LPAR1 (0.59) | LPAR1MAPTLMNATSHRMAPK1 | |
| SCHEMBL1560349 | 0.88 | LPAR1 (0.59) | LPAR1MAPTLMNATSHRMAPK1 | |
| SCHEMBL18832679 | 0.85 | LPAR1 (0.48) | LPAR1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL18832654 | 0.83 | LPAR1 (0.63) | LPAR1 | |
| SCHEMBL18832675 | 0.78 | LPAR1 (0.61) | LPAR1MEN1KMT2AGPR132 | |
| SCHEMBL18832661 | 0.78 | LPAR1 (0.60) | LPAR1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18832673 | 0.78 | LPAR1 (0.51) | LPAR1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL18832678 | 0.78 | LPAR1 (0.63) | LPAR1MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL18832659 | 0.77 | LPAR1 (0.44) | LPAR1MAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18874187 | 0.77 | LPAR1 (0.44) | LPAR1MAPTTSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |