Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560342 | 0.88 | LPAR1 (0.62) | LPAR1NPC1RAB9ANAMPT | |
| SCHEMBL18832654 | 0.86 | LPAR1 (0.63) | LPAR1NPC1RAB9AACHEHDAC1 | |
| SCHEMBL18832673 | 0.85 | LPAR1 (0.51) | LPAR1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL18832668 | 0.85 | LPAR1 (0.46) | LPAR1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18832675 | 0.81 | LPAR1 (0.61) | LPAR1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL18832678 | 0.80 | LPAR1 (0.63) | LPAR1NPC1RAB9ALMNAACHE | |
| SCHEMBL18832661 | 0.80 | LPAR1 (0.60) | LPAR1LMNASMN1; SMN2POLB | |
| SCHEMBL1561248 | 0.80 | LPAR1 (0.51) | LPAR1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1811720 | 0.79 | LPAR1 (0.60) | LPAR1 | |
| SCHEMBL18832674 | 0.79 | LPAR1 (0.60) | LPAR1NPC1RAB9ALMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |