Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832654 | 0.92 | LPAR1 (0.63) | LPAR1 | |
| SCHEMBL18832675 | 0.90 | LPAR1 (0.61) | LPAR1 | |
| SCHEMBL18832662 | 0.88 | LPAR1 (0.60) | LPAR1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL1560224 | 0.88 | LPAR1 (0.77) | LPAR1POLBCASP6LMNANPSR1 | |
| SCHEMBL18832657 | 0.87 | LPAR1 (0.79) | LPAR1MAPT | |
| SCHEMBL18832658 | 0.86 | LPAR1 (0.58) | LPAR1ALDH1A1 | |
| SCHEMBL18832664 | 0.86 | LPAR1 (0.58) | LPAR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18832678 | 0.86 | LPAR1 (0.63) | LPAR1LMNAMAPTALDH1A1 | |
| SCHEMBL18832674 | 0.85 | LPAR1 (0.60) | LPAR1LMNAMAPTALDH1A1 | |
| SCHEMBL18832660 | 0.84 | LPAR1 (0.59) | LPAR1CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |