Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932241 | 0.90 | FGFR1 (0.42) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL3934348 | 0.88 | FGFR1 (0.40) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL13374049 | 0.86 | AMY1A (0.33) | FGFR1FGFR2FGFR3KDRFLT1 | |
| Trifluoroacetic Acid SCHEMBL4127209 | 0.86 | FGFR1 (0.39) | FGFR1FGFR2FGFR3KDROPRL1 | |
| Trifluoroacetic Acid SCHEMBL4133711 | 0.84 | FGFR1 (0.38) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL18833114 | 0.84 | FGFR1 (0.48) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL4295308 | 0.83 | FGFR1 (0.42) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL3926103 | 0.81 | OPRL1 (0.42) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL4129282 | 0.81 | FGFR1 (0.43) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL4130323 | 0.81 | FGFR1 (0.41) | FGFR1FGFR2FGFR3KDREGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041119-B1 | PYRAZOLYLBENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA SA (FR) | 2017-05-10 | — | — | EP | disclosed |