Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 5/20 | 0.39 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.39 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505349 | 0.88 | TRPC5 (0.48) | TRPC5TRPC1TRPC4P2RX3PDE5A | |
| SCHEMBL21499694 | 0.85 | TRPC5 (0.43) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL21499690 | 0.80 | P2RX3 (0.39) | TRPC5TRPC4P2RX3PDE5A | |
| SCHEMBL18834374 | 0.80 | P2RX3 (0.38) | TRPC5TRPC4P2RX3PDE5A | |
| SCHEMBL21499689 | 0.79 | PDE5A (0.41) | TRPC5TRPC4P2RX3PDE5APPARG | |
| SCHEMBL21499677 | 0.79 | TRPC5 (0.51) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL21499678 | 0.79 | TRPC5 (0.48) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL21499669 | 0.79 | TRPC5 (0.49) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL21316298 | 0.78 | P2RX3 (0.46) | TRPC5P2RX3PDE5A | |
| SCHEMBL19505090 | 0.77 | TSHR (0.40) | P2RX3PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |