Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 5/20 | 0.48 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.48 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP4X1 | Q8N118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16364030 | 0.79 | TRPC5 (0.47) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL18834234 | 0.78 | TRPC5 (0.43) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL20432257 | 0.77 | TRPC5 (0.50) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL18833767 | 0.77 | TRPC5 (0.51) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL18834618 | 0.76 | TRPC5 (0.54) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL19505209 | 0.76 | TRPC5 (0.52) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL30642043 | 0.75 | TRPC5 (0.53) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL21332654 | 0.74 | TRPC5 (0.52) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL21316291 | 0.74 | TRPC5 (0.54) | TRPC5TRPC4TRPC1CHRM5P2RX3 | |
| SCHEMBL16364000 | 0.74 | TRPC5 (0.48) | TRPC5TRPC4TRPC1CHRM5P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |