Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.43 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.43 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432257 | 0.86 | TRPC5 (0.50) | TRPC5TRPC1TRPC4CHRM5ALDH1A1 | |
| SCHEMBL16364000 | 0.82 | TRPC5 (0.48) | TRPC5TRPC1TRPC4CHRM5P2RX3 | |
| SCHEMBL18834534 | 0.81 | P2RX3 (0.42) | TRPC5TRPC1TRPC4MEN1ALDH1A1 | |
| SCHEMBL19375602 | 0.81 | ADORA3 (0.43) | TRPC5TRPC1TRPC4MEN1ALDH1A1 | |
| SCHEMBL16664751 | 0.78 | TSHR (0.43) | TRPC5TRPC1TRPC4CHRM5MEN1 | |
| SCHEMBL16364030 | 0.78 | TRPC5 (0.47) | TRPC5TRPC1TRPC4CHRM5BRD4 | |
| SCHEMBL18834891 | 0.78 | TRPC5 (0.48) | TRPC5TRPC1TRPC4CHRM5BRD4 | |
| SCHEMBL18833767 | 0.77 | TRPC5 (0.51) | TRPC5TRPC1TRPC4CHRM5BRD4 | |
| SCHEMBL18834618 | 0.77 | TRPC5 (0.54) | TRPC5TRPC1TRPC4CHRM5P2RX3 | |
| SCHEMBL18834196 | 0.74 | ALDH1A1 (0.40) | BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |