Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | HPGD | P15428 | 8/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | ATM | Q13315 | 2/20 | 0.73 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | XBP1 | P17861 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028826 | 0.87 | TSHR (1.00) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16028896 | 0.81 | TSHR (0.84) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18834052 | 0.79 | ATM (0.72) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16027995 | 0.78 | ALDH1A1 (0.63) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16028621 | 0.78 | ATM (0.71) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16028820 | 0.78 | ATM (0.71) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19375412 | 0.78 | ATM (0.71) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16028495 | 0.77 | TSHR (0.67) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16028236 | 0.75 | ATM (0.67) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5075029 | 0.72 | POLB (0.84) | TSHRALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |