SCHEMBL18836699

SCHEMBL18836699

Clc1nc2c(c(Nc3cc(C4CCCC4)[nH]n3)n1)CCC2

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 19/20 0.63
INSR P06213 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15815782 0.96 IGF1R (0.67) IGF1RINSR
SCHEMBL16540730 0.94 IGF1R (0.64) IGF1RINSR
SCHEMBL15831719 0.81 IGF1R (0.65) IGF1RINSR
SCHEMBL15846939 0.80 IGF1R (0.40) IGF1RINSR
SCHEMBL17557314 0.79 IGF1R (0.68) IGF1RINSR
SCHEMBL16540339 0.77 IGF1R (1.00) IGF1RINSR
SCHEMBL16540416 0.77 IGF1R (1.00) IGF1RINSR
SCHEMBL25369530 0.77 IGF1R (0.61) IGF1R
SCHEMBL15814881 0.77 IGF1R (0.48) IGF1RINSR
SCHEMBL17397443 0.77 IGF1R (0.67) IGF1RINSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170130-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2025-05-29 US disclosed
CN-119053590-A Modulators of MYC family protooncogene proteins 纳罗医疗公司 2024-11-29 CN disclosed
WO-2023164611-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2023-08-31 WO disclosed
WO-2023164611-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2023-08-31 WO disclosed
US-20170137410-A1 FUSED CYCLOALKYL-PYRIMIDINE COMPOUNDS AND USES THEREOF MEDIVATION TECHNOLOGIES, INC (US) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170130-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN MYC, MYCBP, MYCBP2 IGF1R 1878/4885INSR 2296/4885
US-20170137410-A1 FUSED CYCLOALKYL-PYRIMIDINE COMPOUNDS AND USES THEREOF DCK, DTYMK, TK1 IGF1R 2770/4885INSR 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.