SCHEMBL18838134

SCHEMBL18838134

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)CCCCO

nearest known ligand 0.87

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.84
▸ EP300 Q09472 3/20 0.80
▸ CHAT P28329 2/20 0.80
▸ AURKA O14965 2/20 0.80
▸ KAT5 Q92993 2/20 0.80
▸ KAT2B Q92831 1/20 0.80
▸ CREBBP Q92793 1/20 0.70
▸ NAA40 Q86UY6 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29806102 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL18925866 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL21314167 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL14918771 0.98 NAA50 (0.84) NAA50EP300CHATAURKAKAT5
SCHEMBL28813886 0.97 NAA50 (0.85) NAA50EP300CHATAURKAKAT5
SCHEMBL21874948 0.97 NAA50 (0.85) NAA50EP300CHATAURKAKAT5
SCHEMBL15018707 0.97 NAA50 (0.85) NAA50EP300CHATAURKAKAT5
SCHEMBL416543 0.97 NAA50 (0.85) NAA50EP300CHATAURKAKAT5
SCHEMBL17279149 0.96 NAA50 (0.86) NAA50EP300CHATAURKAKAT5
SCHEMBL15693003 0.96 NAA50 (0.86) NAA50EP300CHATAURKAKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920254-B2 Methods and materials for producing 5 and 7-carbon monomers INV NYLON CHEMICALS AMERICAS, LLC (US) 2021-02-16 — — US claimed
US-20200283809-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS Invista North America S.á.r.l. 2020-09-10 — — US claimed
EP-3488010-A2 MATERIALS AND METHODS FOR DIRECTING CARBON FLUX AND INCREASED PRODUCTION OF CARBON BASED CHEMICALS INVISTA Textiles (U.K.) Limited (GB) 2019-05-29 — — EP claimed
EP-3374512-A1 POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF INVISTA Textiles (U.K.) Limited (GB) 2018-09-19 — — EP claimed
WO-2018022440-A2 MATERIALS AND METHODS FOR DIRECTING CARBON FLUX AND INCREASED PRODUCTION OF CARBON BASED CHEMICALS INVISTA NORTH AMERICA S.A.R.L. (US) 2018-02-01 — — WO claimed
US-20180023104-A1 MATERIALS AND METHODS FOR DIRECTING CARBON FLUX AND INCREASED PRODUCTION OF CARBON BASED CHEMICALS INV NYLON CHEMICALS AMERICAS, LLC 2018-01-25 — — US claimed
US-20170159086-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA North America S.à.r.l. 2017-06-08 — — US claimed
WO-2017083493-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA NORTH AMERICA S.A.R.L. (US) 2017-05-18 — — WO claimed
WO-2017083656-A1 POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF INVISTA NORTH AMERICA S.A.R.L (US) 2017-05-18 — — WO claimed
EP-3488006-B1 MATERIALS AND METHODS UTILIZING BIOTIN PRODUCING MUTANT HOSTS FOR THE PRODUCTION OF 7-CARBON CHEMICALS INVISTA TEXTILES UK LTD (GB) 2023-06-07 — — EP disclosed
US-11136603-B2 Materials and methods for directing carbon flux and increased production of 7-aminoheptanoic acid or 6-aminohexanoic acid INV NYLON CHEMICALS AMERICAS, LLC (US) 2021-10-05 — — US disclosed
US-10947570-B2 Materials and methods utilizing biotin producing mutant hosts for the production of 7-carbon chemicals INV NYLON CHEMICALS AMERICAS, LLC (US) 2021-03-16 — — US disclosed
US-10920254-B2 Methods and materials for producing 5 and 7-carbon monomers INV NYLON CHEMICALS AMERICAS, LLC (US) 2021-02-16 — — US disclosed
US-10920254-B2 Methods and materials for producing 5 and 7-carbon monomers INV NYLON CHEMICALS AMERICAS, LLC (US) 2021-02-16 — — US disclosed
US-20170159031-A1 POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF INVISTA North America S.à.r.l. 2017-06-08 — — US disclosed
US-20170159086-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA North America S.à.r.l. 2017-06-08 — — US disclosed
US-20170159086-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA North America S.à.r.l. 2017-06-08 — — US disclosed
WO-2017083656-A1 POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF INVISTA NORTH AMERICA S.A.R.L (US) 2017-05-18 — — WO disclosed
WO-2017083493-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA NORTH AMERICA S.A.R.L. (US) 2017-05-18 — — WO disclosed
WO-2017083493-A1 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS INVISTA NORTH AMERICA S.A.R.L. (US) 2017-05-18 — — WO disclosed
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