Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.85 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 3/20 | 0.80 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.80 |
| ▸ | AURKA | O14965 | 2/20 | 0.80 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.80 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.72 |
| ▸ | NAA40 | Q86UY6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21874948 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15018707 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28813886 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL27900338 | 0.97 | NAA50 (0.81) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29806102 | 0.97 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL21314167 | 0.97 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18925866 | 0.97 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL14918771 | 0.97 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18838134 | 0.97 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL16585582 | 0.96 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056488-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA INC (US) | 2022-02-24 | — | — | US | claimed |
| US-20190264241-A1 | BIOSYNTHESIS OF 1,3-BUTANEDIOL | INVISTA NORTH AMERICA S.A.R.L. | 2019-08-29 | — | — | US | claimed |
| EP-3374512-A1 | POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF | INVISTA Textiles (U.K.) Limited (GB) | 2018-09-19 | — | — | EP | claimed |
| EP-3218506-A1 | BIOSYNTHESIS OF 1,3-BUTANEDIOL | Invista Technologies S.à r.l. (CH) | 2017-09-20 | — | — | EP | claimed |
| WO-2017083656-A1 | POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF | INVISTA NORTH AMERICA S.A.R.L (US) | 2017-05-18 | — | — | WO | claimed |
| WO-2016077745-A1 | BIOSYNTHESIS OF 1,3-BUTANEDIOL | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2016-05-19 | — | — | WO | claimed |
| US-20160138052-A1 | Biosynthesis of 1,3-Butanediol | INV NYLON CHEMICALS AMERICAS, LLC | 2016-05-19 | — | — | US | claimed |
| US-20150152440-A1 | MODIFIED MICROORGANISMS AND METHODS OF CO-PRODUCING BUTADIENE WITH 1-PROPANOL AND/OR 1,2-PROPANEDIOL | BRASKEM S.A. (BR) | 2015-06-04 | — | — | US | claimed |
| WO-2015035244-A1 | MODIFIED MICROORGANISM AND METHODS OF USING SAME FOR PRODUCING BUTADIENE AND 1-PROPANOL AND/OR 1,2-PROPANEDIOL | BRASKEM S/A (BR) | 2015-03-12 | — | — | WO | claimed |
| US-20150064760-A1 | MODIFIED MICROORGANISM AND METHODS OF USING SAME FOR PRODUCING BUTADIENE AND 1-PROPANOL AND/OR 1,2-PROPANEDIOL | BRASKEM S.A. (BR) | 2015-03-05 | — | — | US | claimed |
| WO-2013192183-A1 | MODIFIED MICROORGANISMS AND METHODS OF CO-PRODUCING BUTADIENE WITH 1-PROPANOL AND/OR 1,2-PROPANEDIOL | BRASKEM S/A AP 09 (BR) | 2013-12-27 | — | — | WO | claimed |
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | disclosed |
| EP-4421181-A2 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | Genomatica, Inc. (US) | 2024-08-28 | — | — | EP | disclosed |
| EP-3741865-B1 | NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY | GENOMATICA INC (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2013090915-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2013-06-20 | — | — | WO | disclosed |
| US-20130109064-A1 | MICROORGANISMS AND METHODS FOR PRODUCING 2,4-PENTADIENOATE, BUTADIENE, PROPYLENE, 1,3-BUTANEDIOL AND RELATED ALCOHOLS | GENOMATICA, INC. | 2013-05-02 | — | — | US | disclosed |
| WO-2013028519-A1 | MICROORGANISMS AND METHODS FOR PRODUCING 2,4-PENTADIENOATE, BUTADIENE, PROPYLENE, 1,3-BUTANEDIOL AND RELATED ALCOHOLS | GENOMATICA, INC. (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20120021478-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | AGAIN BIO APS (DK) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | NAA50 298/4885CHAT 1363/4885EP300 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.