Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838150 | 1.00 | ATM (0.46) | ATMKDM4ES100A4MEN1HSP90AA1 | |
| SCHEMBL18838151 | 1.00 | ATM (0.46) | ATMKDM4ES100A4MEN1HSP90AA1 | |
| SCHEMBL18867268 | 1.00 | ATM (0.46) | ATMKDM4ES100A4MEN1HSP90AA1 | |
| SCHEMBL21860493 | 0.88 | APP (0.45) | KDM4ES100A4MEN1KMT2AEGFR | |
| SCHEMBL18838111 | 0.88 | APP (0.45) | KDM4ES100A4MEN1KMT2AEGFR | |
| SCHEMBL18838109 | 0.88 | APP (0.45) | KDM4ES100A4MEN1KMT2AEGFR | |
| SCHEMBL29623739 | 0.88 | APP (0.45) | KDM4ES100A4MEN1KMT2AEGFR | |
| SCHEMBL18838138 | 0.85 | MAPT (0.48) | KDM4ES100A4EGFRCISD1SLC16A3 | |
| SCHEMBL18867245 | 0.85 | MAPT (0.48) | KDM4ES100A4EGFRCISD1SLC16A3 | |
| SCHEMBL18838135 | 0.85 | MAPT (0.48) | KDM4ES100A4EGFRCISD1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699019-B | Benzofuran derivatives useful in the treatment of central nervous system and other diseases | 华纳巴布科克绿色化学学院有限公司 | 2022-05-10 | — | — | CN | disclosed |